Cell-cycle regulation in immunity, tolerance and autoimmunity

被引：51

作者：

Balomenos, D ^{[1
]}

Martínez-A, C ^{[1
]}

机构：

[1] CSIC, Ctr Nacl Biotecnol, Dept Immunol & Oncol, E-28049 Madrid, Spain

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 11期

关键词：

D O I：

10.1016/S0167-5699(00)01748-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To trigger nn effective immune response, lymphocytes must proliferate. In addition to their direct involvement in cell-cycle progression, cell-cycle regulators might thus control immune functions. Recent evidence suggests that these regulators are essential for T-cell function; we argue that their study will provide cities for dissecting anergy and tolerance mechanisms, as well as for intervention in autoimmune diseases.

引用

页码：551 / 555

页数：5