Synthesis and Rhizopus oryzae mediated enantioselective hydrolysis of α-acetoxy aryl alkyl ketones

被引：52

作者：

Demir, AS ^{[1
]}

Hamamci, H

Tanyeli, C

Akhmedov, IM

Doganel, F

机构：

[1] Middle E Tech Univ, Dept Chem, TR-06531 Ankara, Turkey

[2] Middle E Tech Univ, Dept Biotechnol, TR-06531 Ankara, Turkey

[3] Middle E Tech Univ, Dept Food Engn, TR-06531 Ankara, Turkey

来源：

TETRAHEDRON-ASYMMETRY | 1998年 / 9卷 / 10期

关键词：

D O I：

10.1016/S0957-4166(98)00165-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Mn(OAc)(3) oxidation of aromatic ketones afforded the alpha-acetoxy ketones in good yield. Selective hydrolysis of the acetoxy ketones by the fungus Rhizopus oryzae yields (R)-hydroxy ketones in high enantiomeric excess. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1673 / 1677

页数：5