Nucleophilic reactions of propargyl acetates mediated by titanocene dichloride and magnesium

被引：18

作者：

Yang, FL ^{[1
]}

Zhao, G ^{[1
]}

Ding, Y ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 15期

关键词：

titanocene; homopropargyl alcohol; magnesium;

D O I：

10.1016/S0040-4039(01)00309-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of Cp2TiCL2/Mg with propargyl acetates form allenyl titanium intermediates, which undergo nucleophilic addition reactions to aldehydes or ketones to give homopropargyl alcohols in high yields. Subsequent nucleophilic addition to acetonitrile and nucleophilic substitution with allyl bromide are also mentioned. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2839 / 2841

页数：3

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