JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update

被引：528

作者：

Bryne, Jan Christian ^{[1
]}

Valen, Eivind ^{[2
,3
]}

Tang, Man-Hung Eric ^{[2
,3
]}

Marstrand, Troels ^{[2
,3
]}

Winther, Ole ^{[2
,3
,4
]}

da Piedade, Isabelle ^{[5
]}

Krogh, Anders ^{[2
,3
]}

Lenhard, Boris ^{[1
,6
]}

Sandelin, Albin ^{[2
,3
]}

机构：

[1] Univ Bergen, Comp Biol Unit, Bergen Ctr Computat Sci, N-5008 Bergen, Norway

[2] Univ Copenhagen, Bioinformat Ctr, Dept Mol Biol, DK-2100 Copenhagen, Denmark

[3] Univ Copenhagen, Biotech Res & Innovat Ctr, DK-2100 Copenhagen, Denmark

[4] Tech Univ Denmark, DK-2800 Lyngby, Denmark

[5] Univ Copenhagen, Inst Biol, Ctr Comparat Genom, DK-2100 Copenhagen, Denmark

[6] Univ Bergen, Sars Ctr Marine Mol Biol, N-5008 Bergen, Norway

来源：

NUCLEIC ACIDS RESEARCH | 2008年 / 36卷

关键词：

D O I：

10.1093/nar/gkm955

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

JASPAR is a popular open-access database for matrix models describing DNA-binding preferences for transcription factors and other DNA patterns. With its third major release, JASPAR has been expanded and equipped with additional functions aimed at both casual and power users. The heart of the JASPAR databasethe JASPAR CORE sub-databasehas increased by 12 in size, and three new specialized sub-databases have been added. New functions include clustering of matrix models by similarity, generation of random matrices by sampling from selected sets of existing models and a language-independent Web Service applications programming interface for matrix retrieval. JASPAR is available at http://jaspar.genereg.net.

引用

页码：D102 / D106

页数：5

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