Nucleophilic trifluoromethylation of arylidenemalononitriles

被引：29

作者：

Dilman, Alexander D. ^{[1
]}

Levin, Vitalij V. ^{[1
]}

Belyakov, Pavel A. ^{[1
]}

Struchkova, Marina I. ^{[1
]}

Tartakovsky, Vladimir A. ^{[1
]}

机构：

[1] ND Zelinskii Inst Organ Chem, Moscow 119991, Russia

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 28期

基金：

俄罗斯基础研究基金会;

关键词：

arylidenemalononitriles; Michael reaction; trifluoromethylation;

D O I：

10.1016/j.tetlet.2008.05.039

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method for the nucleophilic trifluoromethylation of arylidenemalononitriles using Me3SiCF3 is described. The reaction is carried out in dimethylformamide in the presence of AcONa as a Lewis base, and affords products of Michael addition in high yield. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：4352 / 4354

页数：3

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