Whole-Mount Imaging Demonstrates Hypervascularity of the Pancreatic Ducts and Other Pancreatic Structures

被引:12
作者
El-Gohary, Yousef
Tulachan, Sidhartha [2 ]
Branca, Maria
Sims-Lucas, Sunder [3 ]
Guo, Ping
Prasadan, Krishna
Shiota, Chiyo
Gittes, George K. [1 ]
机构
[1] Univ Pittsburgh, Med Ctr, Childrens Hosp Pittsburgh, Div Pediat Gen & Thorac Surg,Dept Pediat Surg, Pittsburgh, PA 15260 USA
[2] St Elizabeth Hlth Ctr, Dept Internal Med, Youngstown, OH USA
[3] Univ Pittsburgh, Med Ctr, Childrens Hosp Pittsburgh, Div Nephrol,Dept Pediat, Pittsburgh, PA USA
来源
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY | 2012年 / 295卷 / 03期
关键词
pancreas; pancreatic duct; pancreatic duct gland; islet; vasculature; whole-mount; BETA-CELLS; STEM-CELLS; EX-VIVO; ISLETS; ENDOCRINE; EXOCRINE; MOUSE; DIFFERENTIATION; PROGENITORS; TOMOGRAPHY;
D O I
10.1002/ar.22420
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
Confocal microscopy in combination with commercial software is frequently used to generate three-dimensional images of tissue architecture. Here we report a novel, whole-mount imaging protocol technique that allows detailed three-dimensional imaging of adult pancreatic structures. This technique provides an improved appreciation of the anatomical detail of pancreatic structures and of the relationship between the pancreatic ducts and islets. In addition, imaging of the pancreatic ducts revealed a previously unappreciated high degree of hypervascularity. Anat Rec, 2012. (C) 2012 Wiley Periodicals, Inc.
引用
收藏
页码:465 / 473
页数:9
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