Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine:: Convergent synthesis of the aza-C-nucleoside immucillins

被引：91

作者：

Evans, GB

Furneaux, RH

Hutchison, TL

Kezar, HS

Morris, PE

Schramm, VL

Tyler, PC

机构：

[1] Ind Res Ltd, Carbohydrate Chem, Lower Hutt, New Zealand

[2] Albert Einstein Coll Med, Dept Biochem, Bronx, NY 10461 USA

[3] Biocryst Pharmaceut Inc, Birmingham, AL 35244 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 17期

关键词：

D O I：

10.1021/jo0155613

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Means have been developed for the synthesis and addition of 9-deaza-9-lithiopurine derivatives to the carbohydrate-derived cyclic imine 6 in facile convergent syntheses of biologically active aza-C-nucleosides.

引用

页码：5723 / 5730

页数：8

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