Development of 2,2-dimethylchromanol cysteinyl LT1 receptor antagonists

被引：7

作者：

Chambers, RJ ^{[1
]}

Antognoli, GW ^{[1
]}

Cheng, JB ^{[1
]}

Kuperman, AV ^{[1
]}

Liston, TC ^{[1
]}

Marfat, A ^{[1
]}

Owens, BS ^{[1
]}

Pillar, JS ^{[1
]}

Shirley, JT ^{[1
]}

Watson, JW ^{[1
]}

机构：

[1] Pfizer Inc, Div Cent Res, Groton, CT 06340 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 24期

关键词：

D O I：

10.1016/S0960-894X(98)00654-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new series of cysLT(1) receptor antagonists represented by CP-288,886 (7) and CP-265,298 (8) were developed which are equipotent to clinical cysLT(1) receptor antagonists Zafirlukast (1) and Pranlukast (2). (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3577 / 3582

页数：6

共 24 条

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