Antifungal metabolites from the plant endophytic fungus Pestalotiopsis foedan

被引:137
作者
Ding, Gang [1 ,2 ,3 ]
Liu, Shuchun [1 ,2 ]
Guo, Liangdong [1 ,2 ]
Zhou, Yuguang [1 ,2 ]
Che, Yongsheng [1 ,2 ]
机构
[1] Chinese Acad Sci, Inst Microbiol, Key Lab Systemat Mycol & Lichenol, Beijing 100080, Peoples R China
[2] Chinese Acad Sci, Inst Microbiol, Ctr Bioenergy & Ind Biotechnol, Beijing 100080, Peoples R China
[3] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
来源
JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 04期
关键词
D O I
10.1021/np070590f
中图分类号
Q94 [植物学];
学科分类号
071001 [植物学];
摘要
Pestafolide A (1), a new reduced spiro azaphilone derivative, and pestaphthalides A (2) and B (3), two new isobenzofuranones, have been isolated form solid cultures of an isolate of Pestalotiopsis foedan. The structures of these compounds were determined mainly by analysis of their NMR spectroscopic data. The relative configuration of 1-3 was assigned by analysis of H-1 NMR J-values and NOESY data, and the absolute configuration was determined by application of the CD excitation chirality and modified Mosher method. Compounds 1-3 showed modest antifungal activity.
引用
收藏
页码:615 / 618
页数:4
相关论文
共 34 条
[1]
A novel alkaloid serantrypinone and the spiro azaphilone daldinin D from Penicillium thymicola [J].
Ariza, MR ;
Larsen, TO ;
Petersen, BO ;
Duus, JO ;
Christophersen, C ;
Barrero, AF .
JOURNAL OF NATURAL PRODUCTS, 2001, 64 (12) :1590-1592
[2]
Assante G., 1990, PHYTOCHEMISTRY, V29, P613
[3]
Absolute configuration of the fungal metabolite spirolaxine [J].
Bava, A ;
Clericuzio, M ;
Giannini, G ;
Malpezzi, L ;
Meille, SV ;
Nasini, G .
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2005, 2005 (11) :2292-2296
[4]
Curvicollides A-C:: New polyketide-derived lactones from a sclerotium-colonizing isolate of Podospora curvicolla (NRRL 25778) [J].
Che, YS ;
Gloer, JB ;
Wicklow, DT .
ORGANIC LETTERS, 2004, 6 (08) :1249-1252
[5]
Phomadecalins A-D and phomapentenone A:: New bioactive metabolites from Phoma sp NRRL 25697, a fungal colonist of Hypoxylon stromata [J].
Che, YS ;
Gloer, JB ;
Wicklow, DT .
JOURNAL OF NATURAL PRODUCTS, 2002, 65 (03) :399-402
[6]
Decipinin A and decipienolides A and B:: New bioactive metabolites from the coprophilous fungus Podospora decipiens [J].
Che, YS ;
Gloer, JB ;
Koster, B ;
Malloch, D .
JOURNAL OF NATURAL PRODUCTS, 2002, 65 (06) :916-919
[7]
Acetophthalidin, a novel inhibitor of mammalian cell cycle, produced by a fungus isolated from a sea sediment [J].
Cui, CB ;
Ubukata, M ;
Kakeya, H ;
Onose, R ;
Okada, G ;
Takahashi, I ;
Isono, K ;
Osada, H .
JOURNAL OF ANTIBIOTICS, 1996, 49 (02) :216-219
[8]
CJ-12,954 and its congeners, new anti-Helicobacter pylori compounds produced by Phanerochaete velutina: Fermentation, isolation, structural elucidation and biological activities [J].
Dekker, KA ;
Inagaki, T ;
Gootz, TD ;
Kaneda, K ;
Nomura, E ;
Sakakibara, T ;
Sakemi, S ;
Sugie, Y ;
Yamauchi, Y ;
Yoshikawa, N ;
Kojima, N .
JOURNAL OF ANTIBIOTICS, 1997, 50 (10) :833-839
[9]
Caryophyllene sesquiterpenoids from a fungicolous isolate of Pestalotiopsis disseminata [J].
Deyrup, ST ;
Swenson, DC ;
Gloer, JB ;
Donald, TW .
JOURNAL OF NATURAL PRODUCTS, 2006, 69 (04) :608-611
[10]
Natural products from plant-associated microorganisms: Distribution, structural diversity, bioactivity, and implications of their occurrence [J].
Gunatilaka, AAL .
JOURNAL OF NATURAL PRODUCTS, 2006, 69 (03) :509-526