Semiconductor nanocrystals for biological imaging

被引：154

作者：

Fu, AH

Gu, WW

Larabell, C

Alivisatos, AP ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

[2] Univ Calif San Francisco, Dept Anat, San Francisco, CA 94143 USA

[3] Lawrence Berkeley Natl Lab, Phys Biosci Div, Berkeley, CA 94720 USA

[4] Lawrence Berkeley Natl Lab, Div Mat Sci, Berkeley, CA 94720 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2005年 / 15卷 / 05期

关键词：

D O I：

10.1016/j.conb.2005.08.004

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Conventional organic fluorophores suffer from poor photo stability, narrow absorption spectra and broad emission spectra. Semiconductor nanocrystals, however, are highly photo-stable with broad absorption spectra and narrow size-tunable emission spectra. Recent advances in the synthesis of these materials have resulted in the generation of bright, sensitive, extremely photo-stable and biocompatible semiconductor fluorophores. Commercial availability facilitates their application in a variety of unprecedented biological experiments, including multiplexed cellular imaging, long-term in vitro and in vivo labeling, deep tissue structure mapping and single particle investigation of dynamic cellular processes. Semiconductor nanocrystals are one of the first examples of nanotechnology enabling a new class of biomedical applications.

引用

页码：568 / 575

页数：8

共 46 条

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