Reevaluating the role of vascular changes in the differential diagnosis of Alzheimer's disease and vascular dementia

被引:33
作者
Gold, G
Giannakopoulos, P
Bouras, C
机构
[1] HUG, Dept Geriatr, Belle Idee, Switzerland
[2] HUG, Dept Psychiat, Belle Idee, Switzerland
[3] Univ Geneva, Sch Med, CH-1211 Geneva, Switzerland
关键词
Alzheimer's disease; clinical criteria; neuroimaging; neuropathology; review; risk factors; vascular dementia;
D O I
10.1159/000007968
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Alzheimer's disease (AU) and vascular dementia (VaD) are the two most common causes of dementia, and much effort has been devoted to their differential diagnosis. However, current epidemiological, clinical and neuropathological evidence points to a substantial overlap between AD and VaD and suggests that vascular pathology, the traditional cornerstone of the differential diagnosis between the two entities, may not represent as clear a line of demarcation as originally believed. It may be time to reevaluate the dichotomy between AD and VaD.
引用
收藏
页码:121 / 129
页数:9
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