In vitro comparison of the charge-injection limits of activated iridium oxide (AIROF) and platinum-iridium microelectrodes

被引：128

作者：

Cogan, SF

Troyk, PR

Ehrlich, J

Plante, TD

机构：

[1] EIC Labs Inc, Norwood, MA 02062 USA

[2] IIT, Chicago, IL 60616 USA

来源：

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING | 2005年 / 52卷 / 09期

关键词：

charge-injection; current pulsing; iridium oxide; microelectrode; neural stimulation; platinum-iridium;

D O I：

10.1109/TBME.2005.851503

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The charge-injection limits of activated iridium oxide electrodes (AIROF) and PtIr microelectrodes with similar geometric area and shape have been compared in vitro using a stimulation waveform that delivers cathodal current pulses with current-limited control of the electrode bias potential in the interpulse period. Charge-injection limits were compared over a bias range of 0.1-0.7 V (versus Ag vertical bar AgCl) and pulse frequencies of 20, 50, and 100 Hz. The AIROF was capable of injecting between 4 and 10 times the charge of the PtIr electrode, with a maximum value of 3.9 mC/cm(2) obtained at a 0.7 V bias and 20 Hz frequency.

引用

页码：1612 / 1614

页数：3

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