Synthesis of alkaloid natural products using solid-supported reagents and scavengers

被引:24
作者
Baxendale, IR [1 ]
Ley, SV [1 ]
机构
[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England
关键词
D O I
10.2174/138527205774370513
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Supported reagents and scavengers have become key tools for the synthesis of biologically important molecular entities. The complexity of the target molecules attainable and the synthetic flexibility afforded by these systems now rivals any solution phase approach whilst offering the added advantage of rapid purification and work-up. This short review highlights the application of these immobilized reagents to the preparation of alkaloid natural products.
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页码:1521 / 1534
页数:14
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