Dde - A selective primary amine protecting group: A facile solid phase synthetic approach to polyamine conjugates

被引：95

作者：

Nash, IA ^{[1
]}

Bycroft, BW ^{[1
]}

Chan, WC ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT PHARMACEUT SCI,NOTTINGHAM NG7 2RD,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 15期

关键词：

D O I：

10.1016/0040-4039(96)00344-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ability of the 2-chlorotrityl chloride resin and Dde to act as selective and orthogonal primary amine protecting groups has been utilised in a novel solid phase synthesis of protected symmetrical polyamines from which philanthotoxin-343 and sFTX-3.3 have been synthesised. Copyright (C) 1996 Published by Elsevier Science Ltd

引用

页码：2625 / 2628

页数：4

共 15 条

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[7] BYCROFT BW, UNPUB
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[9] SYNTHESIS AND ASSAY OF HYBRID ANALOGS OF ARGIOTOXIN-636 AND PHILANTHOTOXIN-433 - GLUTAMATE-RECEPTOR ANTAGONISTS
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[10] STRUCTURE AND SYNTHESIS OF A POTENT GLUTAMATE RECEPTOR ANTAGONIST IN WASP VENOM
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