Chiral calix[4]arene-based diphosphites as ligands in the asymmetric hydrogenation of prochiral olefins

被引：35

作者：

Marson, Angelica

Freixa, Zoraida

Kamer, Paul C. J.

van Leeuwen, Piet W. N. M. ^{[1
]}

机构：

[1] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland

[2] Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain

[3] Univ Amsterdam, Vant Hoff Inst Mol Sci, NL-1018 WV Amsterdam, Netherlands

来源：

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY | 2007年 / 29期

关键词：

homogeneous catalysis; stereoselective catalysis; asymmetric hydrogenation; calixarenes; diphosphites;

D O I：

10.1002/ejic.200700764

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Chiral calixarene-based diphosphite ligands 3a-d have been obtained via lower-rim functionalisation of the p-tert-butylcalix[4]arene core. High enantiomeric excesses (up to 94 %) and good activities were obtained in the rhodium-catalyzed asymmetric hydrogenation of prochiral olefins with TADDOL-containing diphosphites 3c,d. This is the first example of chiral calix[4]arene-modified ligands that induce high enantioselectivity in metal-catalysed asymmetric reactions.

引用

页码：4587 / 4591

页数：5

共 46 条

[31] Synthesis of a calix[6]arene-derived diphosphite, its palladium and platinum complexes, and the remarkable activity of (syn-calix[6]arene diphosphite)Pd(CH3) (CH3CN)OTf in carbon monoxide and ethene copolymerization [J].