RETRACTED: Antimicrobial and antileishmanial xanthones from the stem bark of Allanblackia gabonensis (Guttiferae) (Retracted article. See vol. 22, pg. 333, 2008)

被引:16
作者
Azebaze, A. G. B. [1 ]
Ouahouo, B. M. W. [2 ]
Vardamides, J. C. [1 ]
Valentin, A. [3 ]
Kuete, V. [4 ]
Acebey, L. [3 ]
Beng, V. P. [4 ]
Nkengfack, A. E. [2 ]
Meyer, M. [5 ]
机构
[1] Univ Douala, Fac Sci, Dept Chem, Douala, Cameroon
[2] Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon
[3] Univ Toulouse 3, Fac Pharm, UMR 152, IRD UPS, F-31062 Toulouse, France
[4] Univ Yaounde I, Fac Sci, Dept Biochem, Yaounde, Cameroon
[5] CNRS, UMR 5154, USM 0502,MNHN, Lab Chim & Biochim Subst Nat, F-75005 Paris, France
关键词
guttiferae; allanblackia; Allanxanthone D; xanthones; antileishmania and; antimicrobial activities;
D O I
10.1080/14786410701855811
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The phytochemical study of stem bark of Allanblackia gabonensis has resulted in the isolation and characterisation of one new xanthone derivative, named allanxanthone D, together with 10 known compounds, including 6 xanthones derivatives, allanxanthone A, 1,5-dihydroxyxanthone, 1,7-dihydroxyxanthone and 1,3,6,7-tetrahydroxy-2-(3-methylbut-2-enyl)xanthone, forbexanthone, 6-deoxyisojacareubin, one polyisoprenylated benzophenone, guttiferone F, one flavanol, epicathechin, two phytosterols, -sitosterol and campesterol. The structures of these compounds were established on the basis of one- and two-dimensional NMR homo- and hetero-nuclear evidence. These compounds were evaluated for their activity against Leishmania amazonensis in vitro and antimicrobial activities against a range of Gram negative and Gram positive bacteria.
引用
收藏
页码:333 / 341
页数:9
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