A preliminary survey of Atopobium vaginae in women attending the Dunedin gynaecology out-patients clinic:: Is the contribution of the hard-to-culture microbiota overlooked in gynaecological disorders?

被引:11
作者
Burton, JP
Chilcott, CN
Al-Qumber, M
Brooks, HJL
Wilson, D
Tagg, JR
Devenish, C
机构
[1] Univ Otago, Ctr Innovat, BLIS Technol, Dunedin, New Zealand
[2] Univ Otago, Dept Womens & Childrens, Dunedin, New Zealand
[3] Univ Otago, Dept Microbiol & Immunol, Dunedin, New Zealand
关键词
Atopobitan vaginae; bacterial vaginosis;
D O I
10.1111/j.1479-828X.2005.00456.x
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Preliminary studies have indicated that the recently described bacterium Atopobium vaginae may have an association with bacterial vaginosis (BV). Fifty-five women attending the gynaecology out-patient's clinic were tested for the presence of this micro-organism, Gardnerella vaginalis, Mobiluncits and Bacteroides species by polymerase chain reaction (PCR)-based assays. The frequency of detection was 40%. PCR detection of Gardnerella vaginalis with A. vaginae, occurred in 50% of A. vaginae-positive cases. Due to the high detection rate of A. vaginae we believe that it is important to determine whether this and other hard-to-culture microorganisms have a role in gynaecological disorders.
引用
收藏
页码:450 / 452
页数:3
相关论文
共 17 条
[1]   Antimicrobial resistance associated with the treatment of bacterial vaginosis [J].
Beigi, RH ;
Austin, MN ;
Meyn, LA ;
Krohn, MA ;
Hillier, SL .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2004, 191 (04) :1124-1129
[2]   Detection of Atopobium vaginae in postmenopausal worrien by cultivation-independent methods warrants further investigation [J].
Burton, JP ;
Devillard, E ;
Cadieux, PA ;
Hammond, JA ;
Reid, G .
JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (04) :1829-1831
[3]   Evaluation of the bacterial vaginal flora of 20 postmenopausal women by direct (Nugent score) and molecular (polymerase chain reaction and denaturing gradient gel electrophoresis) techniques [J].
Burton, JP ;
Reid, G .
JOURNAL OF INFECTIOUS DISEASES, 2002, 186 (12) :1770-1780
[4]   Lactobacillus strains and vaginal ecology [J].
Cadieux, P ;
Burton, J ;
Gardiner, G ;
Braunstein, I ;
Bruce, AW ;
Kang, CY ;
Reid, G .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 287 (15) :1940-1941
[5]   Novel insight into the vaginal microflora in postmenopausal women under hormone replacement therapy as analyzed by PCR-denaturing gradient gel electrophoresis [J].
Devillard, E ;
Burton, JP ;
Hammond, JA ;
Lam, D ;
Reid, G .
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2004, 117 (01) :76-81
[6]   Use of species-directed 16S rRNA gene PCR primers for detection of Atopobium vaginae in patients with bacterial vaginosis [J].
Ferris, MJ ;
Masztal, A ;
Martin, DH .
JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (12) :5892-5894
[7]   Association of Atopobium vaginae, a recently described metronidazole resistant anaerobe, with bacterial vaginosis -: art. no. 5 [J].
Ferris, MJ ;
Masztal, A ;
Aldridge, KE ;
Fortenberry, D ;
Fidel, PL ;
Martin, DH .
BMC INFECTIOUS DISEASES, 2004, 4 (1)
[8]   In vitro activities of garenoxacin (BMS-284756) against 170 clinical isolates of nine Pasteurella species [J].
Goldstein, EJC ;
Citron, DM ;
Merriam, CV ;
Warren, YA ;
Tyrrell, KL ;
Fernandez, HT .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (09) :3068-3070
[9]   Detection of novel organisms associated with salpingitis, by use of 16S rDNA polymerase chain reaction [J].
Hebb, JK ;
Cohen, CR ;
Astete, SG ;
Bukusi, EA ;
Totten, PA .
JOURNAL OF INFECTIOUS DISEASES, 2004, 190 (12) :2109-2120
[10]  
MALATY BP, 2004, J FAM PRACTICE, V53, P827