A preliminary survey of Atopobium vaginae in women attending the Dunedin gynaecology out-patients clinic:: Is the contribution of the hard-to-culture microbiota overlooked in gynaecological disorders?

被引:11
作者
Burton, JP
Chilcott, CN
Al-Qumber, M
Brooks, HJL
Wilson, D
Tagg, JR
Devenish, C
机构
[1] Univ Otago, Ctr Innovat, BLIS Technol, Dunedin, New Zealand
[2] Univ Otago, Dept Womens & Childrens, Dunedin, New Zealand
[3] Univ Otago, Dept Microbiol & Immunol, Dunedin, New Zealand
关键词
Atopobitan vaginae; bacterial vaginosis;
D O I
10.1111/j.1479-828X.2005.00456.x
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Preliminary studies have indicated that the recently described bacterium Atopobium vaginae may have an association with bacterial vaginosis (BV). Fifty-five women attending the gynaecology out-patient's clinic were tested for the presence of this micro-organism, Gardnerella vaginalis, Mobiluncits and Bacteroides species by polymerase chain reaction (PCR)-based assays. The frequency of detection was 40%. PCR detection of Gardnerella vaginalis with A. vaginae, occurred in 50% of A. vaginae-positive cases. Due to the high detection rate of A. vaginae we believe that it is important to determine whether this and other hard-to-culture microorganisms have a role in gynaecological disorders.
引用
收藏
页码:450 / 452
页数:3
相关论文
共 17 条
[11]  
Marrazzo Jeanne M, 2004, Expert Rev Anti Infect Ther, V2, P913, DOI 10.1586/14789072.2.6.913
[12]   A multiplex polymerase chain reaction-based diagnostic method for bacterial vaginosis [J].
Obata-Yasuoka, M ;
Ba-Thein, W ;
Hamada, H ;
Hayashi, H .
OBSTETRICS AND GYNECOLOGY, 2002, 100 (04) :759-764
[13]   Evidence for a commensal, symbiotic relationship between Gardnerella vaginalis and Prevotella bivia involving ammonia: Potential significance for bacterial vaginosis [J].
Pybus, V ;
Onderdonk, AB .
JOURNAL OF INFECTIOUS DISEASES, 1997, 175 (02) :406-413
[14]  
RODRIGUE Z, 1999, INT J SYST BACTERIOL, V49, P1573
[15]   Cloning of 16S rRNA genes amplified from normal and disturbed vaginal microflora suggests a strong association between Atopobium vaginae, Gardnerella vaginalis and bacterial vaginosis [J].
Verhelst, R ;
Verstraelen, H ;
Claeys, G ;
Verschraegen, G ;
Delanghe, J ;
Van Simaey, L ;
De Ganck, C ;
Temmerman, M ;
Vaneechoutte, M .
BMC MICROBIOLOGY, 2004, 4 (1)
[16]   Culture-independent analysis of vaginal microflora:: The unrecognized association of Atopobium vaginae with bacterial vaginosis [J].
Verstraelen, H ;
Verhelst, R ;
Claeys, G ;
Temmerman, M ;
Vaneechoutte, M .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2004, 191 (04) :1130-1132
[17]   Characterization of vaginal microbial communities in adult healthy women using cultivation-independent methods [J].
Zhou, X ;
Bent, SJ ;
Schneider, MG ;
Davis, CC ;
Islam, MR ;
Forney, LJ .
MICROBIOLOGY-SGM, 2004, 150 :2565-2573