Drug-Coated Balloons for the Prevention of Vascular Restenosis

被引：167

作者：

Gray, William A. ^{[1
]}

Granada, Juan F. ^{[1
]}

机构：

[1] Columbia Univ, Dept Med, Med Ctr, New York, NY USA

来源：

CIRCULATION | 2010年 / 121卷 / 24期

关键词：

balloon; balloon angioplasty; coronary disease; peripheral vascular disease; paclitaxel; restenosis; IN-STENT RESTENOSIS; SUPERFICIAL FEMORAL-ARTERY; LOCAL PACLITAXEL DELIVERY; MUSCLE-CELL PROLIFERATION; ABRUPT VESSEL CLOSURE; CORONARY-ARTERY; ATHEROSCLEROTIC ARTERIES; INTRAMURAL DELIVERY; INTIMAL HYPERPLASIA; ELUTING BALLOON;

D O I：

10.1161/CIRCULATIONAHA.110.936922

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The concept that the balloon delivery of a short burst of an antiproliferative agent to a targeted vessel segment as feasible, safe, and effective has been validated in several preclinical and clinical studies with more in progress but has had some mixed results in selected coronary applications. There is still much to learn about the mechanisms and outcomes of the use of DCB, with the potential for improvements in what must be considered an early phase of the technology. Nevertheless, in a short time span, DCBs have demonstrated the capacity to have a significant impact on the practice of percutaneous cardiovascular intervention. © 2010 American Heart Association, Inc.

引用

收藏

页码：2672 / 2680

页数：9

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