Acute sensory ataxic neuropathy associated with monospecific anti-GD1b IgG antibody

被引：43

作者：

Pan, CL

Yuki, N

Koga, M

Chiang, MC

Hsieh, ST

机构：

[1] Natl Taiwan Univ, Coll Med, Dept Anat & Cell Biol, Taipei 10018, Taiwan

[2] Natl Taiwan Univ Hosp, Dept Neurol, Taipei, Taiwan

[3] Yamaguchi Univ, Sch Med, Dept Neurol, Yamaguchi 753, Japan

来源：

NEUROLOGY | 2001年 / 57卷 / 07期

关键词：

D O I：

10.1212/WNL.57.7.1316

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors describe two patients with acute sensory ataxic neuropathy. Both had a profound loss of proprioception and generalized areflexia. High titers of monospecific anti-GD1b IgG antibody were detected in their sera during the acute phase. Sensory ataxia resolved within 2 weeks after the onset. Taken together with the induction of experimental sensory ataxic neuropathy sensitized with GD1b ganglioside, GD1b may be a target molecule for autoantibody in some patients with acute sensory ataxic neuropathy.

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页码：1316 / 1318

页数：3

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