Intramolecular radical additions to quinolines

被引：30

作者：

Harrowven, DC ^{[1
]}

Sutton, BJ

Coulton, S

机构：

[1] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England

[2] GlaxoSmithKline, Harlow CM19 5AW, Essex, England

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 15期

关键词：

radicals and radical reactions; quinolines; nitrogen heterocycles; cyclisation;

D O I：

10.1016/S0040-4039(01)00321-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper is concerned with intramolecular radical additions to quinolines. Radical additions to C-2, C-3 and C-4 of a quinoline have all been shown to proceed under neutral conditions. In each case formation of heteroaromatic products, rather than dihydroquinolines, was observed (implicating the so called oxidative tin hydride pathway). (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2907 / 2910

页数：4

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