Identification of unique bacterial gene segments from Streptococcus mutans with potential relevance to dental caries by subtraction DNA hybridization

被引：16

作者：

Saxena, D

Li, YH

Caufield, PW

机构：

[1] NYU, Coll Dent, Div Diagnost Infect Dis & Hlth Promot, New York, NY 10010 USA

[2] NYU, Coll Dent, Dept Basic Sci & Craniofacial Biol, New York, NY 10010 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2005年 / 43卷 / 07期

关键词：

D O I：

10.1128/JCM.43.7.3508-3511.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Using DNA subtractive hybridization, 49 unique gene segments were identified from a strain of Streptococcus mutans that was isolated from a patient with severe early childhood caries (S-ECC). Further hybridization with DNA from other S. mutans strains isolated from both caries-active and caries-free subjects yielded five unique sequences of DNA common to strains associated with S-ECC.

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收藏

页码：3508 / 3511

页数：4

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