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Role of the cytoskeleton during leukocyte responses

被引：269
作者：
Vicente-Manzanares, M [1 ]
Sánchez-Madrid, F [1 ]
机构：
[1] Hosp Univ Princesa, Serv Inmunol, Madrid 28006, Spain
来源：
NATURE REVIEWS IMMUNOLOGY | 2004年 / 4卷 / 02期
关键词：
D O I：
10.1038/nri1268
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The cytoskeleton is a cellular network of structural, adaptor and signalling molecules that regulates most cellular functions that are related to the immune response, including migration, extravasation, antigen recognition, activation and phagocytosis by different subsets of leukocytes. Recently, a large number of regulatory elements and structural constituents of the leukocyte cytoskeleton have been identified. In this review, we discuss the composition and regulation of the different cytoskeletal elements and their role in immune responses.
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收藏
页码：110 / 122
页数：13
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