Simultaneous acquisition of sectional and fundus ophthalmic images with spectral-domain optical coherence tomography

被引:160
作者
Jiao, SL [1 ]
Knighton, R [1 ]
Huang, XR [1 ]
Gregori, G [1 ]
Puliafito, CA [1 ]
机构
[1] Univ Miami, Sch Med, Bascom Palmer Eye Inst, Miami, FL 33136 USA
来源
OPTICS EXPRESS | 2005年 / 13卷 / 02期
关键词
D O I
10.1364/OPEX.13.000444
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A high-speed spectral-domain optical coherence tomography (OCT) system was built to image the human retina in vivo. A fundus image similar to the intensity image produced by a scanning laser ophthalmoscope (SLO) was generated from the same spectra that were used for generating the OCT sectional images immediately after the spectra were collected. This function offers perfect spatial registration between the sectional OCT images and the fundus image, which is desired in ophthalmology for monitoring data quality, locating pathology, and increasing reproducibility. This function also offers a practical way to detect eye movements that occur during the acquisition of the OCT image. The system was successfully applied to imaging human retina in vivo. (C) 2005 optical Society of America.
引用
收藏
页码:444 / 452
页数:9
相关论文
共 15 条
[1]   High-resolution optical coherence tomography-guided laser ablation of surgical tissue [J].
Boppart, SA ;
Herrmann, J ;
Pitris, C ;
Stamper, DL ;
Brezinski, ME ;
Fujimoto, JG .
JOURNAL OF SURGICAL RESEARCH, 1999, 82 (02) :275-284
[2]   Ultrahigh-resolution high-speed retinal imaging using spectral-domain optical coherence tomography [J].
Cense, B ;
Nassif, NA ;
Chen, T ;
Pierce, M ;
Yun, SH ;
Park, BH ;
Bouma, BE ;
Tearney, GJ ;
de Boer, JF .
OPTICS EXPRESS, 2004, 12 (11) :2435-2447
[3]   Optical coherence tomography as a method for identifying benign and malignant microscopic structures in the prostate gland [J].
D'Amico, AV ;
Weinstein, M ;
Li, XD ;
Richie, JP ;
Fujimoto, J .
UROLOGY, 2000, 55 (05) :783-787
[4]   MEASUREMENT OF INTRAOCULAR DISTANCES BY BACKSCATTERING SPECTRAL INTERFEROMETRY [J].
FERCHER, AF ;
HITZENBERGER, CK ;
KAMP, G ;
ELZAIAT, SY .
OPTICS COMMUNICATIONS, 1995, 117 (1-2) :43-48
[5]  
Goodman J., 2000, Statistical Optics
[6]  
Häusler G, 1998, J BIOMED OPT, V3, P21, DOI 10.1117/1.429899
[7]   Image stabilization for scanning laser ophthalmoscopy [J].
Hammer, DX ;
Ferguson, RD ;
Magill, JC ;
White, MA ;
Elsner, AE ;
Webb, RH .
OPTICS EXPRESS, 2002, 10 (26) :1542-1549
[8]   Three-dimensional imaging of the human retina by high-speed optical coherence tomography [J].
Hitzenberger, CK ;
Trost, P ;
Lo, PW ;
Zhou, QY .
OPTICS EXPRESS, 2003, 11 (21) :2753-2761
[9]   OPTICAL COHERENCE TOMOGRAPHY [J].
HUANG, D ;
SWANSON, EA ;
LIN, CP ;
SCHUMAN, JS ;
STINSON, WG ;
CHANG, W ;
HEE, MR ;
FLOTTE, T ;
GREGORY, K ;
PULIAFITO, CA ;
FUJIMOTO, JG .
SCIENCE, 1991, 254 (5035) :1178-1181
[10]   Ultrahigh resolution Fourier domain optical coherence tomography [J].
Leitgeb, RA ;
Drexler, W ;
Unterhuber, A ;
Hermann, B ;
Bajraszewski, T ;
Le, T ;
Stingl, A ;
Fercher, AF .
OPTICS EXPRESS, 2004, 12 (10) :2156-2165