Introduction to Theme "Chromatin, Epigenetics, and Transcription"

被引：26

作者：

Conaway, Joan W. ^{[1
,2
]}

机构：

[1] Stowers Inst Med Res, Kansas City, MO 64110 USA

[2] Univ Kansas, Med Ctr, Dept Biochem & Mol Biol, Kansas City, KS 66160 USA

来源：

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 | 2012年 / 81卷

关键词：

DNA methylation; noncoding RNA; histone modification; RNA polymerase II; elongation; NONCODING RNAS; ELONGATION; INITIATION; CELLS; GENE;

D O I：

10.1146/annurev-biochem-090711-093103

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transcriptional regulation in eukaryotes depends on a complex network of interactions between RNA polymerases and a host of transcription factors and coregulators that control their activity during transcription initiation and elongation. Among these are an enormous variety of enzymes and proteins that modulate chromatin structure via changes in DNA methylation, histone modifications, and nucleosome location. This volume of the Annual Review of Biochemistry contains a set of four reviews addressing the interplay between mechanisms that regulate DNA methylation, chromatin structure, and transcription.

引用

页码：61 / 64

页数：4

共 14 条

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