Zeta potential of microfluidic substrates: 2. Data for polymers

被引:399
作者
Kirby, BJ
Hasselbrink, EF
机构
[1] Sandia Natl Labs, Microfluid Dept, Livermore, CA 94551 USA
[2] Univ Michigan, Dept Engn Mech, Ann Arbor, MI USA
关键词
microfluidic substrates; miniaturization; review; zeta potential;
D O I
10.1002/elps.200305755
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Zeta potential data are reviewed for a variety of polymeric microfluidic substrate materials. Many of these materials currently used for microchip fabrication have only recently been employed for generation of electroosmotic flow. Despite their recent history, polymeric microfluidic substrates are currently used extensively for microchip separations and other techniques, and understanding of the surface zeta potential is crucial for experimental design. This paper proposes the use of pC (the negative logarithm of the counterion concentration) as a useful normalization for the zeta potential on polymer substrates in contact with indifferent univalent counterions. Normalizing zeta by pC facilitates comparison of results from many investigators. The sparseness of available data for polymeric substrates prevents complete and rigorous justification for this normalization; however, it is consistent with double layer and adsorption theory. For buffers with indifferent univalent cations, normalization with the logarithm of the counterion concentration in general collapses data onto a single zeta/pC vs. pH curve, and (with the exception of PMMA) the repeatability of the data is quite encouraging. Normalization techniques should allow improved ability to predict zeta potential performance on microfluidic substrates and compare results observed with different parameters.
引用
收藏
页码:203 / 213
页数:11
相关论文
共 51 条
  • [41] Effect of caged fluorescent dye on the electroosmotic mobility in microchannels
    Ross, D
    Locascio, LE
    [J]. ANALYTICAL CHEMISTRY, 2003, 75 (05) : 1218 - 1220
  • [42] ELECTROPHORESIS IN SYNTHETIC ORGANIC POLYMER CAPILLARIES - VARIATION OF ELECTROOSMOTIC VELOCITY AND ZETA POTENTIAL WITH PH AND SOLVENT COMPOSITION
    SCHUTZNER, W
    KENNDLER, E
    [J]. ANALYTICAL CHEMISTRY, 1992, 64 (17) : 1991 - 1995
  • [43] Surface modification of polymer-based microfluidic devices
    Soper, SA
    Henry, AC
    Vaidya, B
    Galloway, M
    Wabuyele, M
    McCarley, RL
    [J]. ANALYTICA CHIMICA ACTA, 2002, 470 (01) : 87 - 99
  • [44] Zeta-potential measurement using the Smoluchowski equation and the slope of the current-time relationship in electroosmotic flow
    Sze, A
    Erickson, D
    Ren, LQ
    Li, DQ
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2003, 261 (02) : 402 - 410
  • [45] Surface modification and characterization of microfabricated poly(carbonate) devices: manipulation of electroosmotic flow
    Vaidya, B
    Soper, SA
    McCarley, RL
    [J]. ANALYST, 2002, 127 (10) : 1289 - 1292
  • [46] ELECTROKINETIC PROPERTIES OF POLYMER AND GLASS SURFACES IN AQUEOUS-SOLUTIONS - EXPERIMENTAL-EVIDENCE FOR SWOLLEN SURFACE-LAYERS
    VOIGT, A
    WOLF, H
    LAUCKNER, S
    NEUMANN, G
    BECKER, R
    RICHTER, L
    [J]. BIOMATERIALS, 1983, 4 (04) : 299 - 304
  • [47] A novel asymmetric clamping cell for measuring streaming potential of flat surfaces
    Walker, SL
    Bhattacharjee, S
    Hoek, EMV
    Elimelech, M
    [J]. LANGMUIR, 2002, 18 (06) : 2193 - 2198
  • [48] Surface characterization using chemical force microscopy and the flow performance of modified polydimethylsiloxane for microfluidic device applications
    Wang, B
    Abdulali-Kanji, Z
    Dodwell, E
    Horton, JH
    Oleschuk, RD
    [J]. ELECTROPHORESIS, 2003, 24 (09) : 1442 - 1450
  • [49] Effects of alkaline hydrolysis and dynamic coating on the electroosmotic flow in polymeric microfabricated channels
    Wang, SC
    Perso, CE
    Morris, MD
    [J]. ANALYTICAL CHEMISTRY, 2000, 72 (07) : 1704 - 1706
  • [50] Extended electrokinetic characterization of flat solid surfaces
    Werner, C
    Körber, H
    Zimmermann, R
    Dukhin, S
    Jacobasch, HJ
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1998, 208 (01) : 329 - 346