Iron(III)-catalyzed tandem sequential methanol oxidation/aldol coupling

被引：38

作者：

Lecomte, V ^{[1
]}

Bolm, C ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen Klinikum, Inst Organ Chem, D-52074 Aachen, Germany

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2005年 / 347卷 / 11-13期

关键词：

aldol reaction; catalysis; hydrogen peroxide; methanol oxidation;

D O I：

10.1002/adsc.200505163

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Iron (III)-catalyzed methanol oxidations have been performed using hydrogen peroxide as oxidant. Formaldehyde is formed in situ and reacts subsequently with activated ketones to give alpha-hydroxymethyl carbonyl compounds in good yields. As side reactions iron-catalyzed alpha-hydroxylations have been observed.

引用

页码：1666 / 1672

页数：7

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