Allergic Triggers in Atopic Dermatitis

被引:39
作者
Caubet, Jean-Christoph [2 ,3 ]
Eigenmann, Philippe A. [1 ,2 ]
机构
[1] Univ Hosp Geneva, Adult & Child Allergy Unit, CH-1211 Geneva 14, Switzerland
[2] Univ Geneva, Sch Med, CH-1211 Geneva, Switzerland
[3] Mt Sinai Sch Med, Div Pediat Allergy & Immunol, New York, NY USA
关键词
Atopic dermatitis; Eczema; Allergic trigger; Food; Aeroallergens; EOSINOPHIL CATIONIC PROTEIN; TRANSEPITHELIAL ANTIGEN TRANSPORT; CELL-ADHESION MOLECULE-1; PATCH-TEST; FOOD ALLERGY; DOUBLE-BLIND; CONTROLLED-TRIAL; POSITION PAPER; ADULT PATIENTS; SKIN-PRICK;
D O I
10.1016/j.iac.2010.06.002
中图分类号
R392 [医学免疫学];
学科分类号
100108 [医学免疫学];
摘要
Food or environmental allergens play a significant pathogenic role in a subgroup of patients with atopic dermatitis (AD) and can trigger eczema flares. This review focuses on when and which diagnostic and allergen-avoidance measures are beneficial. Diagnosis of allergic triggers may be aided by skin-prick tests measuring serum-specific IgE and/or atopy patch tests (APT) based on the patient's history, and when necessary, oral food challenges (OFC). In a subset of patients, therapeutic measures, such as elimination of the incriminated allergen(s), can lead to marked improvement of AD; this is especially true for food allergens, but can also apply to inhalant allergens.
引用
收藏
页码:289 / +
页数:21
相关论文
共 115 条
[1]
MILK-INDUCED ECZEMA IS ASSOCIATED WITH THE EXPANSION OF T-CELLS EXPRESSING CUTANEOUS LYMPHOCYTE ANTIGEN [J].
ABERNATHYCARVER, KJ ;
SAMPSON, HA ;
PICKER, LJ ;
LEUNG, DYM .
JOURNAL OF CLINICAL INVESTIGATION, 1995, 95 (02) :913-918
[2]
ATOPIC-DERMATITIS AND AEROALLERGEN CONTACT SENSITIVITY [J].
ADINOFF, AD ;
TELLEZ, P ;
CLARK, RAF .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1988, 81 (04) :736-742
[3]
Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report [J].
Akdis, Cezmi A. ;
Akdis, Mubeccel ;
Bieber, Thomas ;
Bindslev-Jensen, Carsten ;
Boguniewicz, Mark ;
Eigenmann, Philippe ;
Hamid, Qutayba ;
Kapp, Alexander ;
Leung, Donald Y. M. ;
Lipozencic, Jasna K. ;
Luger, Thomas A. ;
Muraro, Antonella ;
Novak, Natalija ;
Platts-Mills, Thomas A. E. ;
Rosenwasser, Lanny ;
Scheynius, Annika ;
Simons, F. Estelle R. ;
Spergel, Jonathan ;
Turjanmaa, Kristiina ;
Wahn, Ulrich ;
Weidinger, Stefan ;
Werfel, Thomas ;
Zuberbier, Torsten .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 118 (01) :152-169
[4]
ATHERTON DJ, 1978, LANCET, V1, P401
[5]
Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation [J].
Baud, O ;
Goulet, O ;
Canioni, D ;
Le Deist, F ;
Radford, I ;
Rieu, D ;
Dupuis-Girod, S ;
Cerf-Bensussan, N ;
Cavazzana-Calvo, M ;
Brousse, N ;
Fischer, A ;
Casanova, JL .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (23) :1758-1762
[6]
Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema:: ISAAC [J].
Beasley, R ;
Keil, U ;
von Mutius, E ;
Pearce, N ;
Aït-Khaled, N ;
Anabwani, G ;
Anderson, HR ;
Asher, MI ;
Björkstéin, B ;
Burr, ML ;
Clayton, TO ;
Crane, J ;
Ellwood, P ;
Lai, CKW ;
Mallol, J ;
Martinez, FD ;
Mitchell, EA ;
Montefort, S ;
Robertson, CF ;
Shah, JR ;
Sibbald, B ;
Stewart, AW ;
Strachan, DP ;
Weiland, SK ;
Williams, HC .
LANCET, 1998, 351 (9111) :1225-1232
[7]
Rapid transepithelial antigen transport in rat jejunum: Impact of sensitization and the hypersensitivity reaction [J].
Berin, MC ;
Kiliaan, AJ ;
Yang, PC ;
Groot, JA ;
Taminiau, JAJM ;
Perdue, MH .
GASTROENTEROLOGY, 1997, 113 (03) :856-864
[8]
Berin MC, 1998, J IMMUNOL, V161, P2561
[9]
Milk-induced urticaria is associated with the expansion of T cells expressing cutaneous lymphocyte antigen [J].
Beyer, K ;
Castro, R ;
Feidel, C ;
Sampson, HA .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2002, 109 (04) :688-693
[10]
APPRAISAL OF SKIN-TESTS WITH FOOD EXTRACTS FOR DIAGNOSIS OF FOOD HYPERSENSITIVITY [J].
BOCK, SA ;
LEE, WY ;
REMIGIO, L ;
HOLST, A ;
MAY, CD .
CLINICAL ALLERGY, 1978, 8 (06) :559-564