Chiral C3 epoxides and halohydrins: Their preparation and synthetic application

被引：101

作者：

Kasai, N ^{[1
]}

Suzuki, T ^{[1
]}

Furukawa, Y ^{[1
]}

机构：

[1] Daiso Co Ltd, Res Labs, Amagasaki, Hyogo 660, Japan

来源：

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC | 1998年 / 4卷 / 5-6期

关键词：

chiral; resolution; optically active; epichlorohydrin; 2,3-dichloro-1-propanol; 3-chloro-1,2-propanediol; glycidol; dehalogenation;

D O I：

10.1016/S1381-1177(97)00034-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Epichlorohydrin, 3-chloro-1,2-propanediol and glycidol are versatile chiral C3 syntons in organic synthesis. For the production of these, more efficient and more practical methods are required and many studies have been reported. Ln this review, biological and synthetic preparations of their synthons and microbial dehalogenation of halohydrins connected with the biological methods are described. Several of their synthetic applications are also introduced. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：237 / 252

页数：16

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