Evaluation of the interaction between sodium hypochlorite and chlorhexidine gluconate and its effect on root dentin

被引：84

作者：

Bui, Tung B. ^{[1
]}

Baumgartner, J. Craig ^{[1
]}

Mitchell, John C. ^{[2
]}

机构：

[1] Oregon Hlth & Sci Univ, Sch Dent, Dept Endodontol, Portland, OR 97239 USA

[2] Oregon Hlth & Sci Univ, Dept Biomat & Biomech, Portland, OR 97201 USA

来源：

JOURNAL OF ENDODONTICS | 2008年 / 34卷 / 02期

关键词：

chlorhexidine; interaction of irrigants; precipitate; sodium hypochlorite; ENDODONTIC IRRIGANT; GUTTA-PERCHA; RATS; CARCINOGENICITY; MICE;

D O I：

10.1016/j.joen.2007.11.006

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The combination of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) forms a precipitate. The aim of this study was to evaluate the effect of irrigating root canals with a combination of NaOCl and CHX on root dentin and dentinal tubules by using the environmental scanning electron microscope (ESEM) and a computer program (Photoshop CS2). Forty-four extracted single-rooted human teeth were instrumented and irrigated with both NaOCl and CHX to produce a precipitate. Root canal surfaces were analyzed with the ESEM. The amount of remaining debris and number of patent tubules were determined. There were no significant differences in remaining debris between the negative control group and the experimental groups. There were significantly fewer patent tubules in the experimental groups when compared with the negative control group. The NaOCl/CHX precipitate tends to occlude the dentinal tubules. Until this precipitate is studied further, caution should be exercised when irrigating with NaOCl and CHX.

引用

页码：181 / 185

页数：5

共 21 条

[1] Interaction between sodium hypochlorite and chlorhexidine gluconate [J].

Basrani, Bettina R. ;

Manek, Sheela ;

Sodhi, Rana N. S. ;

Fillery, Edward ;

Manzur, Aldo .

JOURNAL OF ENDODONTICS, 2007, 33 (08) :966-969

[2]

BAUMGARTNER JC, 1987, J ENDODONT, V13, P147

[3] HPLC determination of the antiseptic agent chlorhexidine and its degradation products 4-chloroaniline and 1-chloro-4-nitrobenzene in serum and urine [J].

Below, H ;

Lehan, N ;

Kramer, A .

MICROCHIMICA ACTA, 2004, 146 (02) :129-135

[4]

BYSTROM A, 1981, SCAND J DENT RES, V89, P321

[5] CARCINOGENICITY OF PARA-CHLOROANILINE IN RATS AND MICE [J].

CHHABRA, RS ;

HUFF, JE ;

HASEMAN, JK ;

ELWELL, MR ;

PETERS, AC .

FOOD AND CHEMICAL TOXICOLOGY, 1991, 29 (02) :119-124

[6] In vitro assessment of the immediate and prolonged antimicrobial action of chlorhexidine gel as an endodontic irrigant against Enterococcus faecalis [J].

Dametto, FR ;

Ferraz, CCR ;

Paula, B ;

Gomes, FD ;

Zaia, AA ;

Teixeira, FB ;

de Souza, FJ .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 2005, 99 (06) :768-772

[7] SODIUM-HYPOCHLORITE ACCIDENT - INADVERTENT INJECTION INTO THE MAXILLARY SINUS [J].

EHRICH, DG ;

BRIAN, JD ;

WALKER, WA .

JOURNAL OF ENDODONTICS, 1993, 19 (04) :180-182

[8] Effect of CHX on the decalcifying effect of 10% citric acid, 20% citric acid, or 17% EDTA [J].

González-López, S. ;

Camejo-Aguilar, D. ;

Sanchez-Sanchez, P. ;

Bolanos-Carmona, V. .

JOURNAL OF ENDODONTICS, 2006, 32 (08) :781-784

[9] A COMPARISON OF 2.0-PERCENT CHLORHEXIDINE GLUCONATE AND 5.25-PERCENT SODIUM-HYPOCHLORITE AS ANTIMICROBIAL ENDODONTIC IRRIGANTS [J].

JEANSONNE, MJ ;

WHITE, RR .

JOURNAL OF ENDODONTICS, 1994, 20 (06) :276-278

[10] EFFECTS OF SURGICAL EXPOSURES OF DENTAL PULPS IN GERM-FREE AND CONVENTIONAL LABORATORY RATS [J].

KAKEHASHI, S ;

STANLEY, HR ;

FITZGERALD, RJ .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 1965, 20 (03) :340-+

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