Synthesis and Characterization of Star-Shaped Porphyrin-Cored Poly(L-lactide)

被引：7

作者：

Dai, Xiao-Hui ^{[1
]}

Liu, Wei ^{[2
]}

Huang, Ya-Fei ^{[3
]}

Dong, Chang-Ming ^{[2
]}

机构：

[1] Jiangsu Univ, Sch Chem & Chem Technol, Dept Chem Engn, Zhenjiang 212013, Peoples R China

[2] Shanghai Jiao Tong Univ, Sch Chem & Chem Technol, Dept Chem Engn, Shanghai 200240, Peoples R China

[3] Jiangsu Univ, Sch Pharmacy, Dept Chem Pharmacy, Zhenjiang 212013, Peoples R China

来源：

ADVANCED MATERIALS, PTS 1-4 | 2011年 / 239-242卷

基金：

中国国家自然科学基金;

关键词：

Ring-opening polymerization; porphyrin-cored poly(L-lactide); fluorescent property; photodynamic therapy; RING-OPENING POLYMERIZATION; POLYMERS;

D O I：

10.4028/www.scientific.net/AMR.239-242.1703

中图分类号：

TQ [化学工业];

学科分类号：

081705 [工业催化];

摘要：

Star-shaped porphyrin-cored poly(L-lactide) (SPPLLA) was synthesized using a tetra-hydroxyethyl terminated porphyrin as a core initiator and 4-(Dimethylamino)pyridine (DMAP) as a catalyst in THF at 50 degrees C. The molecular weight of as-synthesized polymer were measured by GPC and (HNMR)-H-1. It was found that the molecular weight of SPPLLA could be adjusted linearly by controlling the molar ratio of L-lactide to porphyrin core initiator, and the molecular weight distribution was reasonably narrow. Furthermore, SPPLLA polymers showed similar UV-vis spectra compared with porphyrin core initiator. Consequently, this will provide potentially porphyrin-cored poly(L-lactide) for photodynamic therapy.

引用

页码：1703 / +

页数：2

共 12 条

[1]

Recent developments in ring opening polymerization of lactones for biomedical applications [J].