Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis

被引:124
作者
Westrich, L
Domann, S
Faust, B
Bedford, D
Hopwood, DA
Bechthold, A
机构
[1] Univ Tubingen, Inst Pharmazeut Biol, D-72076 Tubingen, Germany
[2] John Innes Inst, Norwich NR4 7UH, Norfolk, England
关键词
Streptomyces; angucycline; landomycin; biosynthetic gene cluster;
D O I
10.1111/j.1574-6968.1999.tb13398.x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
From a cosmid library of Streptomyces cyanogenus S136, DNA fragments encompassing approximately 35 kb of the presumed landomycin biosynthetic gene cluster were identified and sequenced, revealing 32 open reading frames most of which could be assigned through data base comparison. (C) 1999 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码:381 / 387
页数:7
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