Determination of Bioactive Constituents in Traditional Chinese Medicines by CE with Electrochemical Detection

被引：43

作者：

Chen, Gang ^{[1
]}

Zhu, Yizhun ^{[2
]}

Wang, Yufeng ^{[3
]}

Xu, Xuejiao ^{[1
]}

Lu, Tao ^{[1
]}

机构：

[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China

[2] Fudan Univ, Sch Pharm, Shanghai 200032, Peoples R China

[3] Univ Texas San Antonio, Dept Biol, San Antonio, TX 78249 USA

来源：

CURRENT MEDICINAL CHEMISTRY | 2006年 / 13卷 / 21期

关键词：

Traditional Chinese medicine; pharmaceutical analysis; capillary electrophoresis; electrochemical detection; amperometry; electrode; bioactive constituent; differentiation;

D O I：

10.2174/092986706778201657

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper reviews the recent advances and the key strategies in capillary electrophoresis (CE) with electrochemical detection (ECD) for separating and detecting a variety of bioactive constituents in traditional Chinese medicines (TCMs). The subjects covered include the separation modes for the CE analysis of the constituents in TCMs, the CE-ECD system, the sample preparations of TCMs, the ECD of TCMs, the applications of CE-ECD in the determination of various bioactive constituents in Chinese medicinal materials and their preparations, the identification and differentiation of TCMs by CE-ECD, and future prospects. It is expected that CE-ECD will become a powerful tool in the herbal medicinal fields and will lead to the creation of truly routine devices for TCM analysis.

引用

页码：2467 / 2485

页数：19

共 95 条

[31] Analysis of Synthetic chemical drugs in adulterated Chinese medicines by capillary electrophoresis/electrospray ionization mass spectrometry [J].

Cheng, HL ;

Tseng, MC ;

Tsai, PL ;

Her, GR .

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2001, 15 (16) :1473-1480

[32] Simultaneous determination of phytoestrogens in different medicinal parts of Sophora japonica L. by capillary electrophoresis with electrochemical detection [J].

Chu, QC ;

Fu, L ;

Wu, T ;

Ye, JN .

BIOMEDICAL CHROMATOGRAPHY, 2005, 19 (02) :149-154

[33] Simultaneous determination of active ingredients in Erigeron breviscapus (Vant.) Hand-Mazz. by capillary electrophoresis with electrochemical detection [J].

Chu, QC ;

Wu, T ;

Fu, LA ;

Ye, JN .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2005, 37 (03) :535-541

[34] Determination and comparison of phytoestrogens in both crude and parched Flos sophorae immaturus by capillary electrophoresis with electrochemical detection [J].

Chu, QC ;

Wu, T ;

Fu, L ;

Ye, JN .

MICROCHIMICA ACTA, 2004, 148 (3-4) :311-315

[35] Determination and differentiation of Flos chrysanthemum based on characteristic electrochemical profiles by capillary electrophoresis with electrochemical detection [J].

Chu, QC ;

Fu, L ;

Guan, YQ ;

Ye, JN .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (26) :7828-7833

[36] Determination and differentiation of two seemingly identical medicinal herbs by capillary electrophoresis with electrochemical detection [J].

Chu, QC ;

Cao, YH ;

Peng, YY ;

Fu, L ;

Ye, JN .

CHROMATOGRAPHIA, 2004, 60 (1-2) :125-130

[37] Determination of active ingredients of Polygonum cuspidatum Sied. et Zucc. by capillary electrophoresis with electrochemical detection [J].

Chu, QC ;

Peng, YY ;

Ye, JN .

ELECTROANALYSIS, 2004, 16 (17) :1434-1438

[38] Determination of flavonoids in Hippophae rhamnoides L. and its phytopharmaceuticals by capillary electrophoresis with electrochemical detection [J].

Chu, QC ;

Qu, WQ ;

Peng, YY ;

Cao, QH ;

Ye, JN .

CHROMATOGRAPHIA, 2003, 58 (1-2) :67-71

[39]

*COMM NAT PHARM, 2005, PHARM PEOPL REP CHIN, V1, P1

[40] Recent advances in analysis of Chinese medical plants and traditional medicines [J].

Drasar, P ;

Moravcova, J .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2004, 812 (1-2) :3-21

← 1 2 3 4 5 6 7 8 9 10 →