Deconjugation of dehydroamino acids:: Stereoselective synthesis of racemic (E)-vinylglycines

被引：19

作者：

Alexander, PA ^{[1
]}

Marsden, SP ^{[1
]}

Subtil, DMM ^{[1
]}

Reader, JC ^{[1
]}

机构：

[1] Univ Leeds, Sch Chem, Leeds LS2 9JT, W Yorkshire, England

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 24期

关键词：

D O I：

10.1021/ol052139q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical and general two-step synthesis of carbamate-protected (E)-vinylglycines from aliphatic aldehydes is reported. The key step involves the kinetic alpha-protonation of dianionic dienolates derived from dehydroamino acids.

引用

页码：5433 / 5436

页数：4

共 18 条

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