Ca2+/calcineurin signalling in cells of the immune system

被引:158
作者
Feske, S
Okamura, H
Hogan, PG
Rao, A
机构
[1] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA
[2] CBR Inst Biomed Res, Boston, MA 02115 USA
关键词
D O I
10.1016/j.bbrc.2003.09.174
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Calcineurin is a serine-threonine - phosphatase that is expressed in a wide variety of tissues and has particularly critical functions in neurons, cardiac and skeletal muscle cells, and lymphocytes. This review focuses on recent studies elucidating the role of Ca2+/calcineurin signalling of the immune system. (C) 2003 Elsevier Inc. All rights reserved.
引用
收藏
页码:1117 / 1132
页数:16
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