A practical asymmetric synthesis of homochiral α-arylglycines

被引：27

作者：

Mellin-Morlière, C

Aitken, DJ

Bull, SD

Davies, SG

Husson, HP

机构：

[1] Univ Paris 05, CNRS, Fac Sci Pharmaceut & Biol, Chim Therapeut Lab, F-75270 Paris, France

[2] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England

[3] Univ Clermont Ferrand 2, Dept Chem, CNRS, Lab SEESIB, F-63177 Clermont Ferrand, France

[4] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 01期

关键词：

D O I：

10.1016/S0957-4166(01)00022-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral alpha -arylglycines in high e.e. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：149 / 155

页数：7

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