Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge stylotella sp.

被引：24

作者：

Brennan, Mary R. ^{[1
]}

Costello, Catherine E. ^{[2
]}

Maleknia, Simin D. ^{[2
]}

Pettit, George R. ^{[3
,4
]}

Erickson, Karen L. ^{[1
]}

机构：

[1] Clark Univ, Gustaf H Carlson Sch Chem & Biochem, Worcester, MA 01610 USA

[2] MIT, Dept Chem, Cambridge, MA 02139 USA

[3] Arizona State Univ, Canc Res Inst, Tempe, AZ 85287 USA

[4] Arizona State Univ, Dept Chem & Biochem, Tempe, AZ 85287 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 03期

关键词：

D O I：

10.1021/np0704856

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new proline-rich cyclodecapeptide, designated stylopeptide 2, has been isolated from a cytotoxic extract of the Papua New Guinea marine sponge Stylotella sp. and found to correspond to structure 1. The structural assignment was based on HRMS collision-induced dissociation tandem mass spectrometry (CID MS/MS), NMR spectroscopic data, and amino acid analysis, which led to assignment of the absolute configuration.

引用

页码：453 / 456

页数：4

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