Diastereoselective trifluoromethylation of chiral N-(tolylsulfinyl)imines in the presence of Lewis bases

被引：48

作者：

Kawano, Y

Mukaiyama, T

机构：

[1] Kitasato Inst, Ctr Basic Res, Kita Ku, Tokyo 11140003, Japan

[2] Kitasato Univ, Kitasato Inst Life Sci, Minato Ku, Tokyo 1088641, Japan

来源：

CHEMISTRY LETTERS | 2005年 / 34卷 / 07期

关键词：

D O I：

10.1246/cl.2005.894

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A diastereoselctive trifluoromethylation of chiral N-(tolylsulfinyl)imines with(trifluoromethyl)trimethylsilane in the presence of Lewis bases such as tetrabutylammonium acetate or phenoxide proceeded smoothly to afford the corresponding tri-fluoromethylated adducts in good yields.

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页码：894 / 895

页数：2

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