Electric and magnetic fields in stem cell research

被引:7
作者
Ahuja, YR
Bhargava, SC
Ratnakar, KS
机构
[1] Vasavi Med & Res Ctr, Dept Mol & Med Genet, Hyderabad 500004, Andhra Pradesh, India
[2] Nizams Inst Med Sci, Stem Cell & Mol Biol Lab, Hyderabad, Andhra Pradesh, India
[3] MG Inst Technol, Dept Elect & Elect Engn, Hyderabad, Andhra Pradesh, India
[4] Nizams Inst Med Sci, Dept Pathol, Hyderabad, Andhra Pradesh, India
[5] Yashoda Hosp, Yashoda Acad Med Educ & Res, Secunderabad, India
关键词
electrical fields; magnetic fields; stem cell research;
D O I
10.1080/15368370500205480
中图分类号
Q [生物科学];
学科分类号
07 [理学]; 0710 [生物学]; 09 [农学];
摘要
Life of vertebrates, including humans, starts with a fertilized egg, the zygote. During early embryonic development at blastocyst stage the stein cells become prominent. These cells, in time, differentiate into approximately 200 types of cells, which form all the organs of the body. In this process of differentiation, various endogenous and exogenous factors are involved. Electromagnetic fields (EMFs) are one of those factors. Among endogenous factors, epigenetic mechanisms are involved in switching genes on and off as and when required for the differentiation of a specific organ. EMFs seem to have a key role in modulating these epigenetic factors. Very little is known of these factors and their interactions; our understanding of these factors would help in harnessing stem cells in regenerative medicine.
引用
收藏
页码:121 / 134
页数:14
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