Efficient Delivery of Gold Nanoparticles by Dual Receptor Targeting

被引：47

作者：

Bhattacharyya, Sanjib ^{[1
]}

Khan, Jameel Ahmad ^{[1
]}

Curran, Geoffry L.

Robertson, J. David ^{[2
,3
]}

Bhattacharya, Resham ^{[1
]}

Mukherjee, Priyabrata ^{[1
,4
]}

机构：

[1] Mayo Clin, Dept Biochem & Mol Biol, Guggenheim Coll Med 1311B, Rochester, MN 55905 USA

[2] Univ Missouri, Dept Chem, Columbia, MO 65211 USA

[3] Univ Missouri, Univ Missouri Res Reactor, Columbia, MO 65211 USA

[4] Mayo Clin, Coll Med, Guggenheim Coll Med 1311B, Ctr Canc, Rochester, MN 55905 USA

来源：

ADVANCED MATERIALS | 2011年 / 23卷 / 43期

关键词：

CANCER; SIZE; SHAPE;

D O I：

10.1002/adma.201102287

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

The fabrication and characterization of a dual receptor targeted system (DRTS) are described. It is demonstrated that DRTS is more efficient at delivering gold nanoparticles (AuNPs) to ovarian cancer cells expressing epidermal growth factor receptor (EGFR) and folate receptor (FR) than their corresponding single-receptor-targeting systems (SRTS). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：5034 / 5038

页数：5

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