Capillary-scale particle-beam liquid chromatography mass spectrometry interface: Can electron ionization sustain the competition?

被引:29
作者
Cappiello, A [1 ]
Famiglini, G [1 ]
机构
[1] Univ Urbino, Ist Sci Chim, I-61029 Urbino, Italy
关键词
D O I
10.1016/S1044-0305(98)00084-1
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Some people look at the particle-beam interface as an object of the past in a changing world of promising new instrumentation. We believe that generating EI spectra, when possible, is a short cut to the solution of many analytical problems. We are convinced that this approach is valid, but the hardware can surely benefit of new ideas in order to follow adequately the rapid technical evolution of mass spectrometry. In the last 5 years, our research group has deeply investigated the functioning of the particle-beam interface and has proposed a few improvements for its performance. In the following pages, this research effort is described with a particular emphasis on the future evolution of the use of the electron ionization of a liquid effluent. (C) 1998 American Society for Mass Spectrometry.
引用
收藏
页码:993 / 1001
页数:9
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