Progress from CASP6 to CASP7

被引:50
作者
Kryshtafovych, Andriy
Fidelis, Krzysztof
Moult, John
机构
[1] Univ Maryland, Maryland Biotechnol Inst, Ctr Adv Res Biotechnol, Rockville, MD 20850 USA
[2] Univ Calif Davis, Genome Ctr, Davis, CA 95616 USA
关键词
protein structure prediction; community wide experiment; CASP;
D O I
10.1002/prot.21769
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This article describes the general quality of models of three dimensional structure submitted to CASP7 and analyzes progress since the previous experiment, primarily using measures that were used in earlier analyses Overall. improvement in model accuracy compared to CASP6 is modest, but there are two developments of note. server performance has moved closer to that of humans, and there has been a significant improvement in the fraction of targets for which the best model is superior to that obtainable using knowledge of a single best template structure.
引用
收藏
页码:194 / 207
页数:14
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