Tat-SIRT1 tango

被引:22
作者
Blazek, Dalibor [1 ,2 ]
Peterlin, B. Matija [1 ,2 ]
机构
[1] Univ Calif San Francisco, Rosalind Russell Med Res Ctr, Dept Med, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Rosalind Russell Med Res Ctr, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
关键词
D O I
10.1016/j.molcel.2008.02.007
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
引用
收藏
页码:539 / 540
页数:2
相关论文
共 10 条
[1]
NF-κB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II [J].
Barboric, M ;
Nissen, RM ;
Kanazawa, S ;
Jabrane-Ferrat, N ;
Peterlin, BM .
MOLECULAR CELL, 2001, 8 (02) :327-337
[2]
Acetylation of ReIA at discrete sites regulates distinct nuclear functions of NF-κB [J].
Chen, LF ;
Mu, YJ ;
Greene, WC .
EMBO JOURNAL, 2002, 21 (23) :6539-6548
[3]
Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain [J].
Dorr, A ;
Kiermer, V ;
Pedal, A ;
Rackwitz, HR ;
Henklein, P ;
Schubert, U ;
Zhou, MM ;
Verdin, E ;
Ott, M .
EMBO JOURNAL, 2002, 21 (11) :2715-2723
[4]
Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-κB, and AP-1 induction [J].
Fortin, JF ;
Barat, C ;
Beauséjour, Y ;
Barbeau, B ;
Tremblay, MJ .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (38) :39520-39531
[5]
Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation [J].
Kwon, Hye-Sook ;
Brent, Michael M. ;
Getachew, Ruth ;
Jayakumar, Prerana ;
Chen, Lin-Feng ;
Schnolzer, Martina ;
McBurney, Michael W. ;
Marmorstein, Ronen ;
Greene, Warner C. ;
Ott, Melanie .
CELL HOST & MICROBE, 2008, 3 (03) :158-167
[6]
Contribution of immune activation to the pathogenesis and transmission of human immunodeficiency virus type 1 infection [J].
Lawn, SD ;
Butera, ST ;
Folks, TM .
CLINICAL MICROBIOLOGY REVIEWS, 2001, 14 (04) :753-777
[7]
SIRT1 regulates HIV transcription via Tat deacetylation [J].
Pagans, S ;
Pedal, A ;
North, BJ ;
Kaehlcke, K ;
Marshall, BL ;
Dorr, A ;
Hetzer-Egger, C ;
Henklein, P ;
Frye, R ;
McBurney, MW ;
Hruby, H ;
Jung, M ;
Verdin, E ;
Ott, M .
PLOS BIOLOGY, 2005, 3 (02) :210-220
[8]
Controlling the elongation phase of transcription with P-TEFb [J].
Peterlin, B. Matija ;
Price, David H. .
MOLECULAR CELL, 2006, 23 (03) :297-305
[9]
Sirtuins: critical regulators at the crossroads between cancer and aging [J].
Saunders, L. R. ;
Verdin, E. .
ONCOGENE, 2007, 26 (37) :5489-5504
[10]
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase [J].
Yeung, F ;
Hoberg, JE ;
Ramsey, CS ;
Keller, MD ;
Jones, DR ;
Frye, RA ;
Mayo, MW .
EMBO JOURNAL, 2004, 23 (12) :2369-2380