Nickel-catalysed sequential amination of aryl- and heteroaryl di- and trichlorides

被引：30

作者：

Desmarets, C ^{[1
]}

Schneider, R ^{[1
]}

Fort, Y ^{[1
]}

机构：

[1] Univ Nancy 1, Fac Sci Synth Organ & React, UMR CNRS UHP 7565, F-54506 Vandoeuvre Les Nancy, France

来源：

TETRAHEDRON | 2001年 / 57卷 / 36期

关键词：

nickel-catalysed amination; aryl trichlorides; diamino-benzenes; diamino-pyridines; triamino-pyridines;

D O I：

10.1016/S0040-4020(01)00730-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Unsymmetrical 1,3-diaminobenzenes and diaminopyridines, were efficiently prepared by reaction of 3-chloroanilines and chloro-aminopyridines with amines via a nickel-catalysed amination. The Ni/2,2'-bipyridine catalyst is also effective for the sequential amination of aryl trichlorides. After a first selective monoamination of 1,3,5-trichlorobenzene, the obtained 3,5-dichloroanilines were subsequently transformed into novel and unsymmetrical 1,3,5-triaminobenzenes. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：7657 / 7664

页数：8

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