Synthetic studies on V-ATPase inhibiting macrolide antibiotics

被引:8
作者
Toshima, K [1 ]
机构
[1] Keio Univ, Fac Sci & Technol, Dept Appl Chem, Yokohama, Kanagawa 2238522, Japan
关键词
D O I
10.2174/1385272043486043
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthetic studies on the specific inhibitors of vacuolar-type H+-ATPase, bafilomycins, hygrolidines, and concanamycins, are described. Bafilomycins and hygrolidins are 16-membered and concanamycins are 18-membered plecomacrolides, which have very complex molecular structures.
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页码:185 / 210
页数:26
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