A new design for light-breakable polymer micelles

被引：396

作者：

Jiang, JQ ^{[1
]}

Tong, X ^{[1
]}

Zhao, Y ^{[1
]}

机构：

[1] Univ Sherbrooke, Dept Chim, Sherbrooke, PQ J1K 2R1, Canada

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 23期

关键词：

D O I：

10.1021/ja0521019

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new and general design strategy is presented for amphiphilic block copolymers whose micellar aggregates can be dissociated by light. A diblock copolymer composed of hydrophilic poly(ethylene oxide) (PEO) and a hydrophobic polymethacrylate bearing pyrene pendant groups (PPy) was synthesized using ATRP. Upon UV light irradiation of polymer micellar solutions, the photosolvolysis of pyrene moieties results in their detachment from the polymer and converts the hydrophobic PPy block into hydrophilic poly(methacrylic acid). This effect leads to complete dissociation of polymer micelles. Copyright © 2005 American Chemical Society.

引用

页码：8290 / 8291

页数：2

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