Polyhedral oligomeric silsesquioxane nanocomposites: The next generation material for biomedical applications

被引:379
作者
Kannan, RY
Salacinski, HJ
Butler, PE
Seifalian, AM
机构
[1] UCL, BTEC, London, England
[2] Royal Free Hampstead NHS Trust Hosp, London, England
关键词
D O I
10.1021/ar050055b
中图分类号
O6 [化学];
学科分类号
0703 [化学];
摘要
The unique properties of nanocomposites have seen them creating the next revolution in materials science. Their quantal properties as a result of their size have given them unique physical characteristics, previously not possible because of classical physical laws. There is now evidence that these may also extend into the world of biology and medicine. In this Account, we look at the birth of a new generation of silica nanocomposites using polyhedral oligomeric silsesquioxanes, a promising nanoscale silica particle with particular use in cardiovascular interventional devices.
引用
收藏
页码:879 / 884
页数:6
相关论文
共 67 条
[1]
Semiconductor clusters, nanocrystals, and quantum dots [J].
Alivisatos, AP .
SCIENCE, 1996, 271 (5251) :933-937
[2]
Interfacial adsorption of fibrinogen and its inhibition by RGD peptide: a combined physical study [J].
Armstrong, J ;
Salacinski, HJ ;
Mu, QS ;
Seifalian, AM ;
Peel, L ;
Freeman, N ;
Holt, CM ;
Lu, JR .
JOURNAL OF PHYSICS-CONDENSED MATTER, 2004, 16 (26) :S2483-S2491
[3]
Beyer G., 2002, PLASTICS, V4, P22, DOI DOI 10.1016/S1464-391X(02)80151-9
[4]
A Contribution to the Theory of Electrocapillarity [J].
Chapman, David Leonard .
PHILOSOPHICAL MAGAZINE, 1913, 25 (148) :475-481
[5]
Calculations of linear and nonlinear optical properties of H-silsesquioxanes [J].
Cheng, WD ;
Xiang, KH ;
Pandey, R ;
Pernisz, UC .
JOURNAL OF PHYSICAL CHEMISTRY B, 2000, 104 (29) :6737-6742
[6]
Nanoscale anionic macromolecules for selective retention of low-density lipoproteins [J].
Chnari, E ;
Lari, HB ;
Tian, L ;
Uhrich, KE ;
Moghe, PV .
BIOMATERIALS, 2005, 26 (17) :3749-3758
[7]
Organic/inorganic hybrid composites from cubic silsesquioxanes [J].
Choi, J ;
Harcup, J ;
Yee, AF ;
Zhu, Q ;
Laine, RM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (46) :11420-11430
[8]
Effect of single wall carbon nanotubes on human HEK293 cells [J].
Cui, DX ;
Tian, FR ;
Ozkan, CS ;
Wang, M ;
Gao, HJ .
TOXICOLOGY LETTERS, 2005, 155 (01) :73-85
[9]
Polyhedral oligomeric silsesquioxanes: A new class of amphiphiles at the air/water interface [J].
Deng, JJ ;
Polidan, JT ;
Hottle, JR ;
Farmer-Creely, CE ;
Viers, BD ;
Esker, AR .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (51) :15194-15195
[10]
Silsesquioxane models for geminal silica surface silanol sites. A spectroscopic investigation of different types of silanols [J].
Dijkstra, TW ;
Duchateau, R ;
van Santen, RA ;
Meetsma, A ;
Yap, GPA .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (33) :9856-9864