Oxidative Spirocyclization of Phenolic Sulfonamides: Scope and Applications

被引：68

作者：

Liang, Huan ^{[1
]}

Ciufolini, Marco A. ^{[1
]}

机构：

[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2010年 / 16卷 / 44期

基金：

加拿大自然科学与工程研究理事会;

关键词：

alkaloids; dearomatization; lepadiformine; phenols; sulfonamides; TRICYCLIC MARINE ALKALOIDS; ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; HYPERVALENT IODINE OXIDATION; FORMAL TOTAL-SYNTHESIS; DIELS-ALDER REACTIONS; NATURAL ENANTIOMER; LEPADIFORMINE; AMIDATION; (+/-)-LEPADIFORMINE; (-)-LEPADIFORMINE;

D O I：

10.1002/chem.201001402

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A full account of the oxidative dearomatization of para- and ortho-phenolic sulfonamides is provided together with an overview of the chemistry of the products and their elaboration to building blocks for spirocyclic alkaloids. A concise total synthesis of putative lepadiformine complements the discussion.

引用

页码：13262 / 13270

页数：9

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