A quality-effects model for meta-analysis

被引：206

作者：

Doi, Suhail A. R. ^{[1
,3
]}

Thalib, Lukman ^{[2
]}

机构：

[1] Kuwait Univ, Dept Med, Safat 13110, Kuwait

[2] Kuwait Univ, Dept Community Med Biostat, Safat 13110, Kuwait

[3] Mubarak Al Kabeer Teaching Hosp, Div Endocrinol, Safat, Kuwait

来源：

EPIDEMIOLOGY | 2008年 / 19卷 / 01期

关键词：

D O I：

10.1097/EDE.0b013e31815c24e7

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We introduce a quality-effects approach that combines evidence from a series of trials comparing 2 interventions. This approach incorporates the heterogeneity of effects in the analysis of the overall interventional efficacy. However, unlike the random-effects model based on observed between-trial heterogeneity, we suggest adjustment based on measured methodological heterogeneity between studies. We propose a simple noniterative procedure for computing the combined effect size under this model and suggest that this could represent a more convincing alternative to the random effects model.

引用

页码：94 / 100

页数：7

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