Ruthenium-Catalyzed C-H Bond Functionalizations of 1,2,3-Triazol-4-yl-Substituted Arenes: Dehydrogenative Couplings Versus Direct Arylations

被引：86

作者：

Ackermann, Lutz ^{[1
]}

Novak, Petr ^{[1
]}

Vicente, Ruben ^{[1
]}

Pirovano, Valentina ^{[1
]}

Potukuchi, Harish K. ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

SYNTHESIS-STUTTGART | 2010年 / 13期

关键词：

arylations; C-H activation; dehydrogenation; ruthenium; triazoles; ARYL CHLORIDES; CARBON-HYDROGEN; AROMATIC-COMPOUNDS; PHOSPHINE OXIDES; 1,2,3-TRIAZOLES; ACTIVATION; PRELIGANDS; CYCLOADDITION; BROMIDES; HALIDES;

D O I：

10.1055/s-0029-1220010

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The chemoselectivity of ruthenium-catalyzed C-H bond arylations on triazol-4-yl-substituted arenes was found to depend on the substitution pattern of both substrates. While various aryl chlorides led to products stemming from direct arylations, ortho-substituted aryl halides in combination with ortho-alkylated arenes preferentially resulted in oxidative homo-couplings.

引用

页码：2245 / 2253

页数：9

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